Controlled Clinical Studies of Orally Administered Antiemetic Drugs
نویسندگان
چکیده
منابع مشابه
Lymphatic transport of orally administered drugs.
Several therapeutic molecules such as lipophilic drugs and peptides suffer from the problems of low oral bioavailability. Improvement of their bioavailability and simultaneous prevention of the oral degradation of the prone molecules appears to be a challenge. Lymphatic system, which is responsible for the maintenance of fluid balance, immunity and metastatic spread of cancers, is also found to...
متن کاملReview of published studies of orally administered asbestos.
There has been great public concern about the adverse health effects resulting from the presence of asbestos fibers in municipal drinking water supplies. This article reviews and summarizes the experimental findings of 11 published papers that have evaluated the carcinogenic potential of asbestos following its ingestion. The long-term, high-level ingestion of various types of asbestos fibers in...
متن کاملDetection of Orally Administered
Chromatographic analysis of amantadine was achieved using an Agilent J&W CP-Sil 8 CB column. Published by Elsevier B. V. Spatial Reorganization of Saccharomyces cerevisiae Enolase To Alter Carbon Metabolism under Hypoxia Eukaryotic Cell, 12, 1106-1119 (2013) Natsuko Miura et al. Tags CP-Sil 8 CB, clinical research Abstract Derivatized metabolites in a study of yeast hypoxia were analyzed by GC/...
متن کاملVolunteer and clinical studies with carfecillin: a new orally administered ester of carbenicillin.
Blood and urine levels of carbenicillin were measured in 10 healthy volunteers and four patients with renal failure after single and multiple oral dose of carfecillin. Urinary levels after 1000-mg doses in healthy subjects were considered sufficient for treatment of Pseudomonas aeruginosa urinary infections, but the serum levels were too low for chemotherapy of systemic infections with this org...
متن کاملNew antiemetic drugs.
BACKGROUND Important progress in the prophylaxis of chemotherapy-induced acute and delayed emesis has been achieved but some fundamental needs still remain that requires new, efficacious antiemetic drugs. METHODS A critical review of the results of published studies of aprepitant, a new NK1 receptor antagonist, and of palonosetron, a 5-HT3 receptor antagonist with a longer half-life. RESULT...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gastroenterology
سال: 1969
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(19)33898-3